Basic Drug Info
Drug Name:Acetaminophen and Codeine Phosphate
Manufacturer:Pharmaceutical Associates, Inc.
Other Info:Acetaminophen:      toxic dose 10 gCodeine:                 toxic dose 240 mg

Clinical Trials:

Indications and Usage
Acetaminophen and codeine phosphate oral solution is indicated for the relief of mild to moderate pain.
Pain -- An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

This product should not be administered to patients who have previously exhibited hypersensitivity to codeine or acetaminophen.
Hypersensitivity -- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.


In the presence of head injury or other intracranial lesions, the respiratory depressant effects of codeine and other narcotics may be markedly enhanced, as well as their capacity for elevating cerebrospinal fluid pressure.

Narcotics also produce other CNS depressant effects, such as drowsiness, that may further obscure the clinical course of the patients with head injuries.Codeine or other narcotics may obscure signs on which to judge the diagnosis or clinical course of patients with acute abdominal conditions.Codeine is habit-forming and potentially abusable.

Consequently, the extended use of this product is not recommended.

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