|Drug Name:||Lidocaine Hydrochloride and Dextrose|
|Manufacturer:||Baxter Healthcare Corporation|
hydrochloride administered intravenously is specifically indicated in
the acute management of (1) ventricular arrhythmias occurring during
cardiac manipulations, such as cardiac surgery and (2) life-threatening
arrhythmias which are ventricular in origin, such as occur during acute
-- Irregular heart beat resulting from a pathologic process in the cardiac ventricles.--2004
-- any variation from the normal rhythm or rate of the heart beat.
Acute myocardial infarction
hydrochloride is contraindicated in patients with a known history of
hypersensitivity to local anesthetics of the amide type.
should not be used in patients with Stokes-Adams syndrome,
Wolff-Parkinson-White syndrome, or with severe degrees of sinoatrial,
atrioventricular, or intraventricular block.Solutions
containing dextrose may be contraindicated in patients with known
allergy to corn or corn products.
-- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
SPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
-- A condition of fainting spells caused by heart block, often an atrioventricular block, that leads to BRADYCARDIA and drop in CARDIAC OUTPUT. When the cardiac output becomes too low, the patient faints (SYNCOPE). In some cases, the syncope attacks are transient and in others cases repetitive and persistent.
-- A form of ventricular pre-excitation characterized by a short PR interval and a long QRS interval with a delta wave. In this syndrome, atrial impulse conducts to the HEART VENTRICLES via an accessory pathway located between the wall of the right or left atria and the ventricles, known as the bundle of Kent. The inherited form can be caused by mutation of PRKAG2 gene encoding a gamma-2 regulatory subunit of AMP-activated protein kinase.
Intraventricular conduction defect
-- Hypersensitivity reactions which occur within minutes of exposure to challenging antigen due to the release of histamine which follows the antigen-antibody reaction and causes smooth muscle contraction and increased vascular permeability.
with an electrocardiograph is essential to the proper administration of
lidocaine hydrochloride intravenously.
Signs of excessive depression of
cardiac conductivity, such as prolongation of the PR interval, widening
of the QRS interval and the appearance or aggravation of arrhythmias,
should be followed by prompt cessation of the intravenous infusion of this agent.
It is mandatory to have emergency resuscitative equipment
and drugs immediately available to manage adverse reactions involving
cardiovascular, respiratory, or central nervous systems.
acceleration of ventricular rate may occur when lidocaine hydrochloride
is administered to patients with atrial fibrillation.
proper usage in children is limited.
Lidocaine Hydrochloride and 5% Dextrose Injection, USP only with a
calibrated infusion device.
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