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Basic Drug Info
Drug Name:Gentamicin Sulfate
Manufacturer:Perrigo New York
Other Info:MANUFACTUREDBY PERRIGOBRONX, NY 104571C800 RC J2



Clinical Trials:


Indications and Usage

Primary skin infections: Impetigo contagiosa, superficial folliculitis, ecthyma, furunculosis, sycosis barbae, and pyoderma gangrenosum.

Secondary skin infections: Infectious eczematoid dermatitis, pustular acne, pustular psoriasis, infected seborrheic dermatitis, infected contact dermatitis (including poison ivy), infected excoriations, and bacterial superinfections of fungal or viral infections.

NOTE: Gentamicin is a bactericidal agent that is not effective against viruses or fungi in skin infections.

It is useful in the treatment of infected skin cysts and certain other skin abscesses when preceded by incision and drainage to permit adequate contact between the antibiotic and the infecting bacteria.

Good results have been obtained in the treatment of infected stasis and other skin ulcers, infected superficial burns, paronychia, infected insect bites and stings, infected lacerations and abrasions and wounds from minor surgery.

Patients sensitive to neomycin can be treated with GENTAMICIN, although regular observation of patients sensitive to topical antibiotics is advisable when such patients are treated with any topical antibiotic.

GENTAMICIN CREAM is recommended for wet, oozing primary infections, and greasy, secondary infections, such as pustular acne or infected seborrheic dermatitis, and where a water washable cream preparation is desired.

GENTAMICIN OINTMENT helps retain moisture and has been useful in infection on dry eczematous or psoriatic skin.

GENTAMICIN CREAM and OINTMENT have been used successfully in infants over one year of age as well as in adults and children.
Superficial folliculitis --

Furunculosis -- A persistent skin infection marked by the presence of furuncles, often chronic and recurrent. In humans, the causative agent is various species of STAPHYLOCOCCUS. In salmonid fish (SALMONIDS), the pathogen is AEROMONAS SALMONICIDA.

Sycosis barbae --

Pyoderma gangrenosum -- An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.

Infective eczematoid dermatitis --

Pustular psoriasis --

Seborrheic dermatitis -- A chronic inflammatory disease of the skin with unknown etiology. It is characterized by moderate ERYTHEMA, dry, moist, or greasy (SEBACEOUS GLAND) scaling and yellow crusted patches on various areas, especially the scalp, that exfoliate as dandruff. Seborrheic dermatitis is common in children and adolescents with HIV INFECTIONS.

Contact Dermatitis -- A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.

Poison Ivy Dermatitis --

INFECTION SUPERIMPOSED -- A frequent complication of drug therapy for microbial infection. It may result from opportunistic colonization following immunosuppression by the primary pathogen and can be influenced by the time interval between infections, microbial physiology, or host resistance. Experimental challenge and in vitro models are sometimes used in virulence and infectivity studies.

Virus Diseases -- A general term for diseases produced by viruses.

skin infection -- Skin diseases caused by bacteria, fungi, parasites, or viruses.

Cyst;skin;infected --

Abscess of skin AND/OR subcutaneous tissue --

Skin Ulcer -- lesion on the surface of the skin produced by the sloughing of inflammatory necrotic tissue.

Paronychia Inflammation -- An inflammatory reaction involving the folds of the skin surrounding the fingernail. It is characterized by acute or chronic purulent, tender, and painful swellings of the tissues around the nail, caused by an abscess of the nail fold. The pathogenic yeast causing paronychia is most frequently Candida albicans. Saprophytic fungi may also be involved. The causative bacteria are usually Staphylococcus, Pseudomonas aeruginosa, or Streptococcus. (Andrews' Diseases of the Skin, 8th ed, p271)

Oozing (Hemorrhage) --

secondary infection -- infection by a microorganism following an infection by another kind of microorganism.

Communicable Diseases -- broad class of diseases whose causative agents may be passed between individuals in many different ways.

Infection -- Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.

Contraindications
This product, GENTAMICIN OINTMENT AND CREAM is contraindicated in individuals with a history of sensitivity reactions to any of its components.
Branded Drugs
The following US Branded drugs contain Gentamicin Sulfate


GARAMYCIN -- SCHERING CORP SUB SCHERING PLOUGH CORP

GENTAFAIR -- PHARMAFAIR INC

GENTAMICIN -- PERRIGO NEW YORK INC

APOGEN -- KING PHARMACEUTICALS INC

BRISTAGEN -- BRISTOL LABORATORIES INC DIV BRISTOL MYERS CO

GENTAMICIN -- INTERNATIONAL MEDICATION SYSTEMS LTD

GENTAMICIN SULFATE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER -- B BRAUN MEDICAL INC

GENTAMICIN SULFATE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER -- HOSPIRA INC

ISOTONIC GENTAMICIN SULFATE IN PLASTIC CONTAINER -- BAXTER HEALTHCARE CORP

U-GENCIN -- PHARMACIA AND UPJOHN CO

GENTACIDIN -- NOVARTIS PHARMACEUTICALS CORP

GENOPTIC -- ALLERGAN

GENTAK -- AKORN INC

PRED-G -- ALLERGAN PHARMACEUTICAL


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