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Basic Drug Info
Drug Name:Hydrochlorothiazide
Manufacturer:West-ward Pharmaceutical Corp.
Other Info:

For Control of Hypertension- The adult initial dose of hydrochlorothiazide is one capsule given once daily whether given alone or in combination with other antihypertensives.

Total daily doses greater than 50 mg are not recommended.



Clinical Trials:


Indications and Usage

Hydrochlorothiazide capsules are indicated in the management of hypertension either as the sole therapeutic agent, or in combination with other antihypertensives.

Unlike potassium sparing combination diuretic products, hydrochlorothiazide may be used in those patients in whom the development of hyperkalemia cannot be risked, including patients taking ACE inhibitors.
Hypertensive disease -- Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Contraindications

Hydrochlorothiazide is contraindicated in patients with anuria.

Hypersensitivity to this product or other sulfonamide derived drugs is also contraindicated.
Anuria -- Absence of urine formation. It is usually associated with complete bilateral ureteral (URETER) obstruction, complete lower urinary tract obstruction, or unilateral ureteral obstruction when a solitary kidney is present.

Hypersensitivity -- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Warnings
Diabetes and Hypoglycemia: Latent diabetes mellitus may become manifest and diabetic patients given thiazides may require adjustment of their insulin dose.
Branded Drugs
The following US Branded drugs contain Hydrochlorothiazide


TEKTURNA HCT -- NOVARTIS PHARMACEUTICALS CORP

AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- BARR LABORATORIES INC

AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

AMILORIDE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

HYDRO-RIDE -- PAR PHARMACEUTICAL INC

MODURETIC 5-50 -- MERCK RESEARCH LABORATORIES DIV MERCK CO INC

EXFORGE HCT -- NOVARTIS PHARMACEUTICALS CORP

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- GENPHARM INC

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- RANBAXY LABORATORIES LTD

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

BENAZEPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC FLORIDA

LOTENSIN HCT -- NOVARTIS PHARMACEUTICALS CORP

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- ACTAVIS ELIZABETH LLC

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

BISOPROLOL FUMARATE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

ZIAC -- DURAMED PHARMACEUTICALS INC SUB BARR LABORATORIES INC

ATACAND HCT -- ASTRAZENECA PHARMACEUTICALS LP

CAPOZIDE 25/15 -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

CAPOZIDE 25/25 -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

CAPOZIDE 50/15 -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

CAPOZIDE 50/25 -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

CAPTOPRIL AND HYDROCHLOROTHIAZIDE -- ENDO LABORATORIES LLC

CAPTOPRIL AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

CAPTOPRIL AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

CAPTOPRIL AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

CAPTOPRIL AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

ORETICYL 25 -- ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

ORETICYL 50 -- ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

ORETICYL FORTE -- ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- APOTEX INC ETOBICOKE SITE

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- DR REDDYS LABORATORIES LTD

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- TARO PHARMACEUTICAL INDUSTRIES LTD

ENALAPRIL MALEATE AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

VASERETIC -- BIOVAIL LABORATORIES INTERNATIONAL SRL

TEVETEN HCT -- ABBOTT LABORATORIES

FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE -- GENPHARM INC

FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE -- RANBAXY LABORATORIES LTD

FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

FOSINOPRIL SODIUM AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC FLORIDA

MONOPRIL-HCT -- BRISTOL MYERS SQUIBB

ESIMIL -- NOVARTIS PHARMACEUTICALS CORP

APRESAZIDE -- NOVARTIS PHARMACEUTICALS CORP

HYDRALAZINE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- SOLVAY PHARMACEUTICALS

HYDRALAZINE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- SUPERPHARM CORP

HYDRALAZINE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

HYDRALAZINE HYDROCHLORIDE W/ HYDROCHLOROTHIAZIDE 100/50 -- IVAX PHARMACEUTICALS INC

HYDRALAZINE HYDROCHLORIDE W/ HYDROCHLOROTHIAZIDE 25/25 -- IVAX PHARMACEUTICALS INC

HYDRALAZINE HYDROCHLORIDE W/ HYDROCHLOROTHIAZIDE 50/50 -- IVAX PHARMACEUTICALS INC

HYDRA-ZIDE -- PAR PHARMACEUTICAL INC

APRESOLINE-ESIDRIX -- NOVARTIS PHARMACEUTICALS CORP

HYDRALAZINE AND HYDROCHLORTHIAZIDE -- WATSON LABORATORIES INC

HYDROCHLOROTHIAZIDE W/ HYDRALAZINE -- WATSON LABORATORIES INC

CAM-AP-ES -- TG UNITED LABS LLC

HYDRALAZINE HYDROCHLORIDE, HYDROCHLOROTHIAZIDE AND RESERPINE -- IVAX PHARMACEUTICALS INC

HYDRALAZINE HYDROCHLORIDE-HYDROCHLOROTHIAZIDE-RESERPINE -- MYLAN PHARMACEUTICALS INC

HYDRALAZINE, HYDROCHLOROTHIAZIDE W/ RESERPINE -- WATSON LABORATORIES INC

HYDRAP-ES -- SANDOZ INC

HYDROCHLOROTHIAZIDE W/ RESERPINE AND HYDRALAZINE -- WATSON LABORATORIES INC

HYDROSERPINE PLUS (R-H-H) -- IVAX PHARMACEUTICALS INC

RESERPINE, HYDRALAZINE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- MUTUAL PHARMACEUTICAL CO INC

RESERPINE, HYDRALAZINE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- SOLVAY PHARMACEUTICALS

RESERPINE, HYDRALAZINE HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

RESERPINE, HYDROCHLOROTHIAZIDE, AND HYDRALAZINE HYDROCHLORIDE -- LEDERLE LABORATORIES DIV AMERICAN CYANAMID CO

SER-A-GEN -- SOLVAY PHARMACEUTICALS

SER-AP-ES -- NOVARTIS PHARMACEUTICALS CORP

UNIPRES -- SOLVAY PHARMACEUTICALS

MICROZIDE -- WATSON LABORATORIES INC

HYDROCHLOROTHIAZIDE INTENSOL -- ROXANE LABORATORIES INC

ESIDRIX -- NOVARTIS PHARMACEUTICALS CORP

HYDRO-D -- HALSEY DRUG CO INC

HYDRODIURIL -- MERCK AND CO INC

ORETIC -- ABBOTT LABORATORIES PHARMACEUTICAL PRODUCTS DIV

ZIDE -- SOLVAY PHARMACEUTICALS

AVALIDE -- SANOFI AVENTIS US LLC

NORMOZIDE -- SCHERING CORP SUB SCHERING PLOUGH CORP

TRANDATE HCT -- GLAXOSMITHKLINE

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- ACTAVIS ELIZABETH LLC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- APOTEX INC ETOBICOKE SITE

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- AUROBINDO PHARMA LTD

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- LUPIN LTD

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- RANBAXY PHARMACEUTICALS INC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- WATSON LABS INC

LISINOPRIL AND HYDROCHLOROTHIAZIDE -- WEST WARD PHARMACEUTICAL CORP

PRINZIDE -- MERCK RESEARCH LABORATORIES DIV MERCK CO INC

ZESTORETIC -- ASTRAZENECA UK LTD

HYZAAR -- MERCK AND CO INC

ALDORIL 15 -- MERCK AND CO INC

ALDORIL 25 -- MERCK AND CO INC

ALDORIL D30 -- MERCK AND CO INC

ALDORIL D50 -- MERCK AND CO INC

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- CLONMEL HEALTHCARE LTD

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- PAR PHARMACEUTICAL INC

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- PARKE DAVIS DIV WARNER LAMBERT CO

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- PUREPAC PHARMACEUTICAL CO

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

METHYLDOPA AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

DUTOPROL -- ASTRAZENECA LP

LOPRESSOR HCT -- NOVARTIS PHARMACEUTICALS CORP

METOPROLOL TARTRATE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

MOEXIPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- PADDOCK LABORATORIES INC

MOEXIPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- TEVA PHARMACEUTICALS USA INC

UNIRETIC -- SCHWARZ PHARMA INC

BENICAR HCT -- DAIICHI SANKYO INC

VISKAZIDE -- NOVARTIS PHARMACEUTICALS CORP

INDERIDE LA 120/50 -- WYETH AYERST LABORATORIES

INDERIDE LA 160/50 -- WYETH AYERST LABORATORIES

INDERIDE LA 80/50 -- WYETH AYERST LABORATORIES

INDERIDE-40/25 -- AKRIMAX PHARMACEUTICALS LLC

INDERIDE-80/25 -- AKRIMAX PHARMACEUTICALS LLC

PROPRANOLOL HYDROCHLORIDE & HYDROCHLOROTHIAZIDE -- DURAMED PHARMACEUTICALS INC SUB BARR LABORATORIES INC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- ACTAVIS ELIZABETH LLC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- BARR LABORATORIES INC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- PLIVA INC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- WARNER CHILCOTT DIV WARNER LAMBERT CO

PROPRANOLOL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

ACCURETIC -- PFIZER PHARMACEUTICALS LTD

QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- AUROBINDO PHARMA LTD

QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

QUINAPRIL HYDROCHLORIDE AND HYDROCHLOROTHIAZIDE -- RANBAXY LABORATORIES LTD

QUINARETIC -- ACTAVIS TOTOWA LLC

H.R.-50 -- WHITEWORTH TOWNE PAULSEN INC

HYDROCHLOROTHIAZIDE W/ RESERPINE -- IVAX PHARMACEUTICALS INC

HYDROCHLOROTHIAZIDE W/ RESERPINE -- PHARMERAL INC

HYDROCHLOROTHIAZIDE W/ RESERPINE -- ROXANE LABORATORIES INC

HYDROCHLOROTHIAZIDE W/ RESERPINE -- WATSON LABORATORIES INC

HYDROPRES 25 -- MERCK AND CO INC

HYDROPRES 50 -- MERCK AND CO INC

HYDRO-RESERP -- ABC HOLDING CORP

HYDRO-SERP "25" -- SANDOZ INC

HYDRO-SERP "50" -- SANDOZ INC

RESERPINE AND HYDROCHLOROTHIAZIDE -- BARR LABORATORIES INC

RESERPINE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

RESERPINE AND HYDROCHLOROTHIAZIDE-50 -- WEST WARD PHARMACEUTICAL CORP

SERPASIL-ESIDRIX #1 -- NOVARTIS PHARMACEUTICALS CORP

SERPASIL-ESIDRIX #2 -- NOVARTIS PHARMACEUTICALS CORP

ALDACTAZIDE -- GD SEARLE LLC

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- ASCOT HOSP PHARMACEUTICALS INC DIV TRAVENOL LABORATORIES INC

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- MUTUAL PHARMACEUTICAL CO INC

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- PUREPAC PHARMACEUTICAL CO

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- SUPERPHARM CORP

SPIRONOLACTONE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- LEDERLE LABORATORIES DIV AMERICAN CYANAMID CO

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- PARKE DAVIS DIV WARNER LAMBERT CO

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- PUREPAC PHARMACEUTICAL CO

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- UPSHER SMITH LABORATORIES INC

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- USL PHARMA INC

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- VANGARD LABORATORIES INC DIV MIDWAY MEDICAL CO

SPIRONOLACTONE W/ HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

MICARDIS HCT -- BOEHRINGER INGELHEIM

TIMOLIDE 10-25 -- MERCK AND CO INC

DYAZIDE -- GLAXOSMITHKLINE

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- BARR LABORATORIES INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- DURAMED PHARMACEUTICALS INC SUB BARR LABORATORIES INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- IVAX PHARMACEUTICALS INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- MYLAN PHARMACEUTICALS INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- NOVARTIS PHARMACEUTICALS CORP

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- SANDOZ INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- VITARINE PHARMACEUTICALS INC

MAXZIDE -- MYLAN BERTEK PHARMACEUTICALS INC

MAXZIDE-25 -- MYLAN BERTEK PHARMACEUTICALS INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- AMERICAN THERAPEUTICS INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- APOTEX INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- PLIVA INC

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- QUANTUM PHARMICS LTD

TRIAMTERENE AND HYDROCHLOROTHIAZIDE -- WATSON LABORATORIES INC

DIOVAN HCT -- NOVARTIS PHARMACEUTICALS CORP


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