|Drug Name:||Priscoline hydrochloride|
|Manufacturer:||Novartis Pharmaceuticals Corporation|
In treating hypotension, it is most important to place the patient’s head low and administer intravenous fluids.Epinephrine should not be used, since large doses of Priscoline may cause “epinephrine reversal” (further reduction in blood pressure, followed by an exaggerated rebound).
Priscoline stimulates gastric secretion and may activate stress ulcers.
Through this mechanism, it can produce significant hypochloremic alkalosis.Pretreatment of infants with antacids may prevent gastrointestinal bleeding.Patients should be observed closely for signs of systemic hypotension, and supportive therapy should be instituted if needed.In patients with mitral stenosis, parenterally administered Priscoline may produce a rise or fall in pulmonary artery pressure and total pulmonary resistance; therefore, it must be used with caution in patients with known or suspected mitral stenosis.