|Drug Name:||Hydroxyzine Hydrochloride|
|Manufacturer:||Morton Grove Pharmaceuticals, Inc.|
Rx OnlyProduct No.: 8150Manufactured By:Morton Grove Pharmaceuticals, Inc.Morton Grove, IL 60053A50-8150-16REV.7-04
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested.Useful in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus.As a sedative when used as premedication and following general anesthesia, hydroxyzine may potentiate meperidine and barbiturates, so their use in pre-anesthetic adjunctive therapy should be modified on an individual basis.
Atropine and other belladonna alkaloids are not affected by the drug.
Hydroxyzine is not known to interfere with the action of digitalis in any way and it may be used concurrently with this agent.The effectiveness of hydroxyzine as an antianxiety agent for long term use, that is more than 4 months, has not been assessed by systematic clinical studies.The physician should reassess periodically the usefulness of the drug for the individual patient.
Hydroxyzine, when administered to the pregnant mouse, rat, and rabbit, induced fetal abnormalities in the rat and mouse at doses substantially above the human therapeutic range.
Clinical data in human beings are inadequate to establish safety in early pregnancy.Until such data are available, hydroxyzine is contraindicated in early pregnancy.Hydroxyzine is contraindicated for patients who have shown a previous hypersensitivity to it.
It is not known whether this drug is excreted in human milk.Since many drugs are so excreted, hydroxyzine should not be given to nursing mothers.