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Basic Drug Info
Drug Name:Dexamethasone Sodium Phosphate
Manufacturer:FALCON Pharmaceuticals, Ltd.
Other Info:



Clinical Trials:


Indications and Usage
For the treatment of the following conditions:
Contraindications
Epithelial herpes simplex keratitis (dendritic keratitis).Acute infectious stages of vaccinia, varicella, and many other viral diseases of the cornea and conjunctiva.Mycobacterial infection of the eye.Fungal diseases of ocular or auricular structures.Hypersensitivity to any component of this product.Perforation of a drum membrane.
Vaccinia -- The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.

Chickenpox -- A highly contagious infectious disease caused by the varicella-zoster virus (HERPESVIRUS 3, HUMAN). It usually affects children, is spread by direct contact or respiratory route via droplet nuclei, and is characterized by the appearance on the skin and mucous membranes of successive crops of typical pruritic vesicular lesions that are easily broken and become scabbed. Chickenpox is relatively benign in children, but may be complicated by pneumonia and encephalitis in adults. (From Dorland, 27th ed)

Virus Diseases -- A general term for diseases produced by viruses.

Corneal Diseases -- Diseases of the cornea.

Mycobacterium Infections -- Infections with bacteria of the genus MYCOBACTERIUM.

Mycoses -- disease caused by a fungus.

Disorder of eye -- impairment of health or a condition of abnormal functioning of the organ of sight.

Hypersensitivity -- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Warnings

Prolonged use may result in ocular hypertension and/or glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation.

Prolonged use may suppress the host response and thus increase the hazard of secondary ocular infections.

In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical corticosteroids.

In acute purulent conditions of the eye or ear, corticosteroids may mask infection or enhance existing infection.

If these products are used for 10 days or longer, intraocular pressure should be routinely monitored even though it may be difficult in children and uncooperative patients.Employment of corticosteroid medication in the treatment of herpes simplex other than epithelial herpes simplex keratitis, in which it is contraindicated, requires great caution; periodic slit-lamp microscopy is essential.
Branded Drugs
The following US Branded drugs contain Dexamethasone Sodium Phosphate


DEXACORT -- UCB INC

DECADRON -- MERCK AND CO INC

DEXACEN-4 -- CENTRAL PHARMACEUTICALS INC

DEXAMETHASONE -- ABRAXIS PHARMACEUTICAL PRODUCTS

HEXADROL -- ORGANON USA INC

DEXAIR -- PHARMAFAIR INC

MAXIDEX -- ALCON LABORATORIES INC

DECADRON W/ XYLOCAINE -- MERCK AND CO INC

NEODECADRON -- MERCK AND CO INC

NEOMYCIN SULFATE AND DEXAMETHASONE SODIUM PHOSPHATE -- BAUSCH AND LOMB PHARMACEUTICALS INC

NEOMYCIN SULFATE-DEXAMETHASONE SODIUM PHOSPHATE -- ALCON UNIVERSAL LTD

NEOMYCIN SULFATE-DEXAMETHASONE SODIUM PHOSPHATE -- PHARMAFAIR INC


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