PRESCRIBING INFORMATION(PHARMACIST - PLEASE REMOVE BEFORE DISPENSING)EPIPEN® 0.3 mg EPINEPHRINE AUTO-INJECTORAuto-Injector for Intramuscular Injection of EpinephrineFor the Emergency Treatment of Allergic Reactions (Anaphylaxis)Delivers a single 0.3 mg intramuscular dose of epinephrine from epinephrine injection, USP, 1:1000 (0.3 mL).EPIPEN® JR 0.15 mg EPINEPHRINE AUTO-INJECTORAuto-Injector for Intramuscular Injection of EpinephrineFor the Emergency Treatment of Allergic Reactions (Anaphylaxis)Delivers a single 0.15 mg intramuscular dose of epinephrine from epinephrine injection, USP, 1:2000 (0.3 mL).IMPORTANT INFORMATIONDO NOT REMOVE GRAY SAFETY RELEASE UNTIL READY FOR USE.A SINGLE DOSE OF 0.3 ML OF SOLUTION IS DISPENSED.THE MAJORITY OF THE DRUG PRODUCT, 1.7 ML, REMAINS IN THE AUTO-INJECTOR AFTER ACTIVATION AND CANNOT BE USED.THE UNIT CONTAINS NO LATEX.
Epinephrine is indicated in the emergency treatment of allergic reactions (anaphylaxis) to insect stings or bites, foods, drugs and other allergens as well as idiopathic or exercise-induced anaphylaxis.
The EpiPen and EpiPen Jr auto-injectors are intended for immediate self-administration by a person with a history of an anaphylactic reaction.
Such reactions may occur within minutes after exposure and consist of flushing, apprehension, syncope, tachycardia, thready or unobtainable pulse associated with a fall in blood pressure, convulsions, vomiting, diarrhea and abdominal cramps, involuntary voiding, wheezing, dyspnea due to laryngeal spasm, pruritis, rashes, uticaria or angioedema.The EpiPen and EpiPen Jr are designed as emergency supportive therapy only and are not a replacement or substitute for immediate medical or hospital care.
Epinephrine is light sensitive and should be stored in the tube provided.
Store at 25°C (77°F); excursions permitted to 15°C-30°C (59°F-86°F) (See USP Controlled Room Temperature).
Do not refrigerate.
Before using, check to make sure the solution in the auto-injector is not discolored.
Replace the auto-injector if the solution is discolored or contains a precipitate.
Avoid possible inadvertent intravascular administration.
EpiPen and EpiPen Jr should only be injected into the anterolateral aspect of the thigh.
DO NOT INJECT INTO BUTTOCK.Large doses or accidental intravenous injection of epinephrine may result in cerebral hemorrhage due to sharp rise in blood pressure.
DO NOT INJECT INTRAVENOUSLY.
Rapidly acting vasodilators can counteract the marked pressor effects of epinephrine.Epinephrine is the preferred treatment for serious allergic or other emergency situations even though this product contains sodium metabisulfite, a sulfite that may in other products cause allergic-type reactions including anaphylactic symptoms or life-threatening or less severe asthmatic episodes in certain susceptible persons.
The alternatives to using epinephrine in a life-threatening situation may not be satisfactory.
The presence of a sulfite in this product should not deter administration of the drug for treatment of serious allergic or other emergency situations.Accidental injection into the hands or feet may result in loss of blood flow to the affectedarea and should be avoided.
If there is an accidental injection into these areas, advise the patient to go immediately to the nearest emergency room for treatment.EpiPen and EpiPen Jr should only be injected into the anterolateral aspect of the thigh.