|Drug Name:||Lidocaine Hydrochloride and Dextrose|
|Other Info:||AmpulSingle-dose ContainerRx only|
5% Lidocaine Hydrochloride and 7.5% Dextrose Injection, USP
is indicated for the production of spinal anesthesia when the accepted procedures
for this technique as described in standard textbooks are observed.
Lidocaine is contraindicated in patients with a known history
of hypersensitivity to local anesthetics of the amide type. The
following conditions preclude the use of spinal anesthesia:Severe hemorrhage, shock or heart blockLocal infection at the site of proposed punctureSepticemiaKnown sensitivity to the local anesthetic agent.
-- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
SPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
-- A pathological condition that can suddenly affect the hemodynamic equilibrium, usually manifested by failure to perfuse or oxygenate vital organs.
-- broad class of diseases whose causative agents may be passed between individuals in many different ways.
-- Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.
5% LIDOCAINE HYDROCHLORIDE AND 7.5% DEXTROSE INJECTION, USP
FOR SPINAL ANESTHESIA SHOULD BE EMPLOYED ONLY BY CLINICIANS WHO ARE WELL VERSED
IN DIAGNOSIS AND MANAGEMENT OF DOSE-RELATED TOXICITY AND OTHER ACUTE EMERGENCIES
THAT MIGHT ARISE FROM SPINAL ANESTHESIA AND THEN ONLY AFTER ENSURING THE IMMEDIATE
AVAILABILITY OF OXYGEN, OTHER RESUSCITATIVE DRUGS, CARDIOPULMONARY EQUIPMENT,
AND THE PERSONNEL NEEDED FOR PROPER MANAGEMENT OF TOXIC REACTIONS AND RELATED
EMERGENCIES (See also ADVERSE REACTIONS and PRECAUTIONS).
DELAY IN PROPER
MANAGEMENT OF DOSE-RELATED TOXICITY, UNDERVENTILATION FROM ANY CAUSE AND/OR
ALTERED SENSITIVITY MAY LEAD TO THE DEVELOPMENT OF ACIDOSIS, CARDIAC ARREST
AND, POSSIBLY, DEATH. To avoid intravascular injection,
aspiration should be performed before the local anesthetic solution is injected.
The needle must be repositioned until no return of blood can be elicited by
Note, however, that the absence of blood in the syringe does not
guarantee that intravascular injection has been avoided. Spinal
anesthetics should not be injected during uterine contractions since spinal
fluid current may carry the drug farther cephalad than desired.
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It should not to be used for self-diagnosis or treatment.