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Basic Drug Info
Drug Name:Ionosol and Dextrose
Manufacturer:Hospira
Other Info:A MAINTENANCE ELECTROLYTE SOLUTIONFlexible Plastic ContainerRx only



Clinical Trials:


Indications and Usage
Ionosol B and 5% Dextrose Injection is indicated for intravenous administration to patients who require a maintenance source of fluid and electrolytes. Ionosol B and 5% Dextrose Injection is used in patients requiring polyionic fluid maintenance, for alkalosis due to vomiting, diabetic acidosis, fluid losses due to burns or stress and postoperative dehydration.
Alkalosis -- A pathological condition that removes acid or adds base to the body fluids.

Vomiting -- The forcible expulsion of the contents of the STOMACH through the MOUTH.

Diabetic Ketoacidosis -- A life-threatening complication of diabetes mellitus, primarily of TYPE 1 DIABETES MELLITUS with severe INSULIN deficiency and extreme HYPERGLYCEMIA. It is characterized by excessive LIPOLYSIS, oxidation of FATTY ACIDS, production of KETONE BODIES, a sweet smell to the breath (KETOSIS;) DEHYDRATION; and depressed consciousness leading to COMA.

Fluid loss --

Dehydration -- The condition that results from excessive loss of water from a living organism.

Contraindications
Solutions containing potassium are contraindicated in diseases where high potassium levels may be encountered.
Disease -- A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.

Warnings

Solutions which contain potassium ions should be used with great care, if at all, in patients with hyperkalemia, severe renal failure and in conditions in which potassium retention is present. Solutions containing sodium ions should be used with great care, if at all, in patients with congestive heart failure, severe renal insufficiency and in clinical states in which there exists edema with sodium retention. In patients with diminished renal function, administration of solutions containing sodium or potassium ions may result in sodium or potassium retention. Solutions containing lactate ions should be used with great care, if at all, in patients with metabolic or respiratory alkalosis.

The administration of lactate ions should be done with great care in those conditions in which there is an increased level or an impaired utilization of lactate ions, such as severe hepatic insufficiency. The intravenous administration of Ionosol B and 5% Dextrose Injection can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary edema. The risk of dilutional states is inversely proportional to the electrolyte concentrations of administered parenteral solutions.

The risk of solute overload causing congested states with peripheral and pulmonary edema is directly proportional to the electrolyte concentrations of such solutions.

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