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Basic Drug Info
Drug Name:Amlodipine Besylate
Manufacturer:Mylan Pharmaceuticals Inc
Other Info:Mylan Pharmaceuticals Inc.Morgantown, WV 26505JANUARY 2005PL:AMDP:R1



Clinical Trials:


Indications and Usage

1.

Hypertension: Amlodipine besylate tablets are indicated for the treatment of hypertension.

They may be used alone or in combination with other antihypertensive agents.
Hypertensive disease -- Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.

Contraindications
Amlodipine besylate tablets are contraindicated in patients with known sensitivity to amlodipine.
Warnings

Rarely, patients, particularly those with severe obstructive coronary artery disease, have developed documented increased frequency, duration and/or severity of angina or acute myocardial infarction on starting calcium channel blocker therapy or at the time of dosage increase.

The mechanism of this effect has not been elucidated.
Branded Drugs
The following US Branded drugs contain Amlodipine Besylate


NORVASC -- PFIZER INC

CADUET -- PFIZER INC

AMLODIPINE BESYLATE AND BENAZEPRIL HYDROCHLORIDE -- TEVA PHARMACEUTICALS USA

LOTREL -- NOVARTIS PHARMACEUTICALS CORP

AZOR -- DAIICHI SANKYO INC

EXFORGE -- NOVARTIS PHARMACEUTICALS CORP


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