When oral therapy is not feasible, and the strength,
dosage form and route of administration of the drug reasonably lend
the preparation to the treatment of the condition, A-Hydrocort sterile
powder is indicated for intravenous or intramuscular use in the following
DisordersPrimary or secondary
adrenocortical insufficiency (hydrocortisone or cortisone is the drug
of choice; synthetic analogs may be used in conjunction with mineralocorticoids
where applicable; in infancy, mineralocorticoid supplementation is
of particular importance)Acute adrenocortical
insufficiency (hydrocortisone or cortisone is the drug of choice;
mineralocorticoid supplementation may be necessary, particularly when
synthetic analogs are used)Preoperatively
and in the event of serious trauma or illness, in patients with known
adrenal insufficiency or when adrenocortical reserve is doubtfulShock unresponsive to conventional therapy if adrenocortical
insufficiency exists or is suspectedCongenital
adrenal hyperplasiaHypercalcemia associated
with cancerNonsuppurative thyroiditisRheumatic DisordersAs adjunctive therapy for short-term
administration (to tide the patient over an acute episode or exacerbation)
in:Post-traumatic osteoarthritisSynovitis of osteoarthritisRheumatoid arthritis, including juvenile rheumatoid arthritis (selected
cases may require low-dose maintenance therapy)Acute and subacute bursitisEpicondylitisAcute nonspecific tenosynovitisAcute gouty arthritisPsoriatic arthritisAnkylosing spondylitisCollagen DiseasesDuring an exacerbation or as maintenance therapy in selected cases
of: Systemic lupus erythematosusSystemic dermatomyositis (polymyositis)Acute rheumatic carditisDermatologic DiseasesPemphigus Severe erythema
multiforme (Stevens-Johnson syndrome)Exfoliative
dermatitisBullous dermatitis herpetiformisSevere seborrheic dermatitis Severe psoriasisMycosis fungoidesAllergic States Control of severe or incapacitating allergic
conditions intractable to adequate trials of conventional treatment
in: Bronchial asthmaContact dermatitisAtopic dermatitisSerum sicknessSeasonal
or perennial allergic rhinitisDrug hypersensitivity
reactionsUrticarial transfusion reactionsAcute noninfectious laryngeal edema (epinephrine
is the drug of first choice)Ophthalmic DiseasesSevere acute and chronic allergic and inflammatory processes involving
the eye, such as: Herpes zoster ophthalmicusIritis, iridocyclitis ChorioretinitisDiffuse posterior uveitis
and choroiditisOptic neuritisSympathetic ophthalmiaAnterior segment inflammationAllergic
conjunctivitis Allergic corneal marginal
ulcers KeratitisGastrointestinal DiseasesTo tide the patient over a critical period of the
disease in:Ulcerative colitis (systemic
therapy)Regional enteritis (systemic therapy)Respiratory Diseases Symptomatic sarcoidosisBerylliosis Fulminating or
disseminated pulmonary tuberculosis when used concurrently with appropriate
syndrome not manageable by other means Aspiration pneumonitisHematologic DisordersAcquired
(autoimmune) hemolytic anemiaIdiopathic
thrombocytopenic purpura in adults (IV only; IM administration is
in adultsErythroblastopenia (RBC anemia)Congenital (erythroid) hypoplastic anemiaNeoplastic DiseasesFor palliative management of: Leukemias and lymphomas in adultsAcute leukemia of childhoodEdematous StatesTo induce diuresis or remission of proteinuria in
the nephrotic syndrome, without uremia, of the idiopathic type or
that due to lupus erythematosusNervous SystemAcute exacerbations of multiple sclerosisMiscellaneous Tuberculous meningitis with subarachnoid block or impending
block when used concurrently with appropriate antituberculous chemotherapy Trichinosis with neurologic or myocardial involvement
Adrenal cortical hypofunction
-- The inability of the adrenal gland to produce adequate amounts of cortisol.
Adrenal gland hypofunction
-- abnormally diminished activity of the adrenal gland.
-- inflammation of the joints; tends to be chronic.
Chronic Childhood Arthritis
-- Rheumatoid arthritis of children occurring in three major subtypes defined by the symptoms present during the first six months following onset: systemic-onset (Still's Disease, Juvenile-Onset), polyarticular-onset, and pauciarticular-onset. Adult-onset cases of Still's disease (STILL'S DISEASE, ADULT-ONSET) are also known. Only one subtype of juvenile rheumatoid arthritis (polyarticular-onset, rheumatoid factor-positive) clinically resembles adult rheumatoid arthritis and is considered its childhood equivalent.
Herpes zoster disease
-- An acute infectious, usually self-limited, disease believed to represent activation of latent varicella-zoster virus (HERPESVIRUS 3, HUMAN) in those who have been rendered partially immune after a previous attack of CHICKENPOX. It involves the SENSORY GANGLIA and their areas of innervation and is characterized by severe neuralgic pain along the distribution of the affected nerve and crops of clustered vesicles over the area. (From Dorland, 27th ed)
-- Inflammation of the choroid as well as the retina and vitreous body. Some form of visual disturbance is usually present. The most important characteristics of posterior uveitis are vitreous opacities, choroiditis, and chorioretinitis.
-- A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
Unspecified pulmonary tuberculosis, unspecified examination
-- MYCOBACTERIUM infections of the lung.
-- A symptom complex of unknown etiology, that is characteristic of a particular abnormality.
Purpura, Thrombocytopenic, Idiopathic
-- Thrombocytopenia occurring in the absence of toxic exposure or a disease associated with decreased platelets. It is mediated by immune mechanisms, in most cases IMMUNOGLOBULIN G autoantibodies which attach to platelets and subsequently undergo destruction by macrophages. The disease is seen in acute (affecting children) and chronic (adult) forms.
-- A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
-- A general term for various neoplastic diseases of the lymphoid tissue.
-- The presence of proteins in the urine, an indicator of KIDNEY DISEASES.
-- A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.
-- A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
SPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
-- Inflammation of the coverings of the brain and/or spinal cord, which consist of the PIA MATER; ARACHNOID; and DURA MATER. Infections (viral, bacterial, and fungal) are the most common causes of this condition, but subarachnoid hemorrhage (HEMORRHAGES, SUBARACHNOID), chemical irritation (chemical MENINGITIS), granulomatous conditions, neoplastic conditions (CARCINOMATOUS MENINGITIS), and other inflammatory conditions may produce this syndrome. (From Joynt, Clinical Neurology, 1994, Ch24, p6)
-- A form of bacterial meningitis caused by MYCOBACTERIUM TUBERCULOSIS or rarely MYCOBACTERIUM BOVIS. The organism seeds the meninges and forms microtuberculomas which subsequently rupture. The clinical course tends to be subacute, with progressions occurring over a period of several days or longer. Headache and meningeal irritation may be followed by SEIZURES, cranial neuropathies, focal neurologic deficits, somnolence, and eventually COMA. The illness may occur in immunocompetent individuals or as an OPPORTUNISTIC INFECTION in the ACQUIRED IMMUNODEFICIENCY SYNDROME and other immunodeficiency syndromes. (From Adams et al., Principles of Neurology, 6th ed, pp717-9)
-- A disease due to infection with TRICHINELLA SPIRALIS. It is caused by eating undercooked meat, usually pork.