|Manufacturer:||Eli Lilly and Company|
|Other Info:||Literature revised April 28, 2005Eli
Lilly and CompanyIndianapolis, IN 46285, USA|
indicated in the treatment of active pulmonary and extrapulmonary tuberculosis
(including renal disease) when the causative organisms are susceptible to
this drug and when treatment with the primary medications (streptomycin, isoniazid,
rifampin, and ethambutol) has proved inadequate.
Like all antituberculosis
drugs, Seromycin should
be administered in conjunction with other effective chemotherapy and not as
the sole therapeutic agent.Seromycin may
be effective in the treatment of acute urinary tract infections caused by
susceptible strains of gram–positive and gram–negative bacteria,
especially Enterobacter spp.
It is generally no more and is usually less effective than
other antimicrobial agents in the treatment of urinary tract infections caused
by bacteria other than mycobacteria.
Use of Seromycin in
these infections should be considered only when more conventional therapy
has failed and when the organism has been demonstrated to be susceptible to
-- Pathological processes of the KIDNEY or its component tissues.
Urinary tract infection
-- Inflammatory responses of the epithelium of the URINARY TRACT to microbial invasions. They are often bacterial infections with associated BACTERIURIA and PYURIA.
-- Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.
Administration is contraindicated in patients with any of the following:
Administration of Seromycin should
be discontinued or the dosage reduced if the patient develops allergic dermatitis
or symptoms of CNS toxicity, such as convulsions, psychosis,
somnolence, depression, confusion, hyperreflexia, headache, tremor, vertigo,
paresis, or dysarthria.
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