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Basic Drug Info
Drug Name:Triamcinolone Acetonide
Manufacturer:E. FOUGERA and CO.
Other Info:

Pharmacokinetics: The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.

Topical corticosteroids can be absorbed from normal intact skin.

Inflammation and/or other disease processes in the skin increase percutaneous absorption.

Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids.

Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses (See DOSAGE AND ADMINISTRATION).

Once absorbed through the skin, topical corticosteroids are handled through pharmacokinetic pathways similar to systemically administered corticosteroids.

Corticosteroids are bound to plasma proteins in varying degrees.

Corticosteroids are metabolized primarily in the liver and are then excreted by the kidneys.

Some of the topical corticosteroids and their metabolites are also excreted into the bile.



Clinical Trials:


Indications and Usage
Topical corticosteroids are indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Dermatologic disorders -- impairment of health or a condition of abnormal functioning of the skin.

Contraindications
Topical corticosteroids are contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Hypersensitivity -- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.

Branded Drugs
The following US Branded drugs contain Triamcinolone Acetonide


MYTREX A -- SAVAGE LABORATORIES INC DIV ALTANA INC

NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE -- E FOUGERA DIV ALTANA INC

NEOMYCIN SULFATE-TRIAMCINOLONE ACETONIDE -- PHARMADERM DIV ALTANA INC

MYCOLOG-II -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

MYCO-TRIACET II -- TEVA PHARMACEUTICALS USA INC

MYKACET -- ACTAVIS MID ATLANTIC LLC

MYTREX F -- SAVAGE LABORATORIES INC DIV ALTANA INC

NYSTATIN AND TRIAMCINOLONE ACETONIDE -- ALPHARMA US PHARMACEUTICALS DIVISION

NYSTATIN AND TRIAMCINOLONE ACETONIDE -- PERRIGO NEW YORK INC

NYSTATIN AND TRIAMCINOLONE ACETONIDE -- PHARMAFAIR INC

NYSTATIN AND TRIAMCINOLONE ACETONIDE -- TARO PHARMACEUTICALS USA INC

NYSTATIN-TRIAMCINOLONE ACETONIDE -- E FOUGERA DIV ALTANA INC

NYSTATIN-TRIAMCINOLONE ACETONIDE -- PHARMADERM DIV ALTANA INC

AZMACORT -- ABBOTT LABORATORIES

NASACORT -- SANOFI AVENTIS US LLC

ARISTOCORT -- ASTELLAS PHARMA US INC

ARISTOCORT A -- ASTELLAS PHARMA US INC

FLUTEX -- IVAX PHARMACEUTICALS INC

KENALOG -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

KENALOG-H -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

TRIACET -- TEVA PHARMACEUTICALS USA INC

TRIACORT -- SOLVAY PHARMACEUTICALS

TRIATEX -- IVAX PHARMACEUTICALS INC

TRIDERM -- DEL RAY LABORATORIES INC

TRYMEX -- SAVAGE LABORATORIES INC DIV ALTANA INC

ARISTOGEL -- ASTELLAS PHARMA US INC

KENALOG-10 -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

KENALOG-40 -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

TRIVARIS -- ALLERGAN INC

TRIESENCE -- ALCON INC

KENALOG -- BRISTOL MYERS SQUIBB CO PHARMACEUTICAL RESEARCH INSTITUTE

TRIAMCINOLONE ACETONIDE IN ABSORBASE -- CAROLINA MEDICAL PRODUCTS CO

KENALOG IN ORABASE -- APOTHECON INC DIV BRISTOL MYERS SQUIBB

ORACORT -- TARO PHARMACEUTICALS USA INC

ORALONE -- TARO PHARMACEUTICALS USA INC

NASACORT AQ -- SANOFI AVENTIS US LLC

NASACORT HFA -- SANOFI AVENTIS US LLC

TRI-NASAL -- COLLEGIUM PHARMACEUTICALS

KENALOG -- RANBAXY LABORATORIES INC


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