Basic Drug Info
Drug Name:Neomycin and Polymyxin B Sulfates and Bacitracin Zinc
Manufacturer:Bausch & Lomb Incorporated
Other Info:Bausch & Lomb IncorporatedTampa, FL 33637┬ęBausch & Lomb IncorporatedXO51065 (Folded)XM10135 (Flat)R.11/03-02

Clinical Trials:

Indications and Usage

Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment is indicated for the topical treatment of superficial infections of the external eye and its adnexa caused by susceptible bacteria.

Such infections encompass conjunctivitis, keratitis and keratoconjunctivitis, blepharitis and blepharoconjunctivitis.
Superficial Infection --

Infection -- Invasion of the host organism by microorganisms that can cause pathological conditions or diseases.

Conjunctivitis -- inflammation of the mucous membrane that lines the inner surface of the eyelids and the anterior part of the sclera; also called pinkeye and redeye.

Keratitis -- Inflammation of the cornea.

Keratoconjunctivitis -- Simultaneous inflammation of the cornea and conjunctiva.

Blepharitis -- Inflammation of the eyelids.

Blepharoconjunctivitis --

Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment is contraindicated in those individuals who have shown hypersensitivity to any of its components.
Hypersensitivity -- Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.


NOT FOR INJECTION INTO THE EYE.Neomycin and polymyxin B sulfates and bacitracin zinc ophthalmic ointment should never be directly introduced into the anterior chamber of the eye.

Ophthalmic ointments may retard corneal wound healing.Topical antibiotics, particularly neomycin sulfate, may cause cutaneous sensitization.

A precise incidence of hypersensitivity reactions (primarily skin rash) due to topical antibiotics is not known.

The manifestations of sensitization to topical antibiotics are usually itching, reddening, and edema of the conjunctiva and eyelid.

A sensitization reaction may manifest simply as a failure to heal.

During long-term use of topical antibiotic products, periodic examination for such signs is advisable, and the patient should be told to discontinue the product if they are observed.

Symptoms usually subside quickly on withdrawing the medication.

Application of products containing these ingredients should be avoided for the patient thereafter (see PRECAUTIONS: General).

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