In a few patients hydralazine may produce a clinical picture simulating systemic lupus erythematosus including glomerulonephritis.
In such patients hydralazine should be discontinued unless the benefit-to-risk determination requires continued antihypertensive therapy with this drug.
Symptoms and signs usually regress when the drug is discontinued but residua have been detected many years later.
Long-term treatment with steroids may be necessary.(See PRECAUTIONS,Laboratory Tests.)