|Drug Name:||Cyproheptadine Hydrochloride|
Adults: The total daily dose for adults should not exceed 0.5 mg/kg/day.
The therapeutic range is 4 to 20 mg a day, with the majority of patients requiring 12 to 16 mg a day.
An occasional patient may require as much as 32 mg a day for adequate relief.
It is suggested that dosage be initiated with 4 mg (1 tablet) three times a day and adjusted according to the size and response of the patient.
INDICATIONS AND USAGEPerennial and seasonal allergic rhinitisVasomotor rhinitisAllergic conjunctivitis due to inhalant allergens and foodsMild, uncomplicated allergic skin manifestations of urticaria and angioedema.Amelioration of allergic reactions to blood or plasmaCold urticariaDermatographismAs therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.
Seasonal allergic conjunctivitis
-- A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.
-- Swelling involving the deep DERMIS, subcutaneous, or submucosal tissues, representing localized EDEMA. Angioedema often occurs in the face, lips, tongue, and larynx.
CONTRAINDICATIONSNewborn or Premature Infants: This drug should not be used in newborn or premature infants.
WARNINGSPediatric Patients: Overdosage of antihistamines, particularly in infants and young children, may produce hallucinations, central nervous system depression, convulsions, respiratory and cardiac arrest, and death.Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation.
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