|Drug Name:||Neomycin and Polymyxin B Sulfates and Dexamethasone|
|Manufacturer:||Bausch & Lomb Incorporated|
|Other Info:||Bausch & Lomb IncorporatedTampa, FL 33637©Bausch & Lomb IncorporatedXO51027 (Folded)XM10097 (Flat)R.12/03-02|
For steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists.Ocular steroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of steroid use in certain cases of infective conjunctivitides is accepted to obtain a diminution in edema and inflammation.They are also indicated in chronic anterior uveitis and corneal injury from chemical radiation or thermal burns; or penetration of foreign bodies.The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.The particular anti-infective drugs in this product is active against the following common bacterial eye pathogens: Staphylococcusaureus, Escherichia coli, Haemophilus influenzae, Klebsiella/Enterobacter species, Neisseria species, Pseudomonas aeruginosa.This product does not provide adequate coverage against Serratia marcescens, and Streptococci, including Streptococcus pneumoniae.
Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella and many other viral diseases of the cornea and conjunctiva.
Mycobacterial infection of the eye.
Fungal diseases of ocular structures.Hypersensitivity to a component of the medication.(Hypersensitivity to the antibiotic component occurs at a higher rate than for other components.)
NOT FOR INJECTION.
Do not touch tube tip to any surface, as this may contaminate the contents.
Prolonged use may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation.
Prolonged use may suppress the host response and thus increase the hazard of secondary ocular infections.
In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids.
In acute purulent conditions of the eye, steroids may mask infection or enhance existing infection.If these products are used for 10 days or longer, intraocular pressure should be routinely monitored even though it may be difficult in children and uncooperative patients.Products containing neomycin sulfate may cause cutaneous sensitization.Employment of steroid medication in the treatment of herpes simplex requires great caution.