Perennial and seasonal allergic rhinitisVasomotor rhinitisAllergic conjunctivitis due to inhalant allergens and foodsMild, uncomplicated allergic skin manifestations of urticaria and angioedemaAmelioration of allergic reactions to blood or plasmaCold urticariaDermatographismAs therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.

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Seasonal allergic conjunctivitis --

Urticaria -- A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

Allergic Reaction --

Newborn or Premature InfantsThis drug should not be used in newborn or premature infants.Nursing MothersBecause of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers.Other ConditionsHypersensitivity to cyproheptadine and other drugs of similar chemical structure:Monoamine oxidase inhibitor therapy (see PRECAUTIONS; Drug Interactions)Angle-closure glaucomaStenosing peptic ulcerSymptomatic prostatic hypertrophyBladder neck obstructionPyloroduodenal obstructionElderly, debilitated patients

Pediatric PatientsOverdosage of antihistamines, particularly in infants and young children, may produce hallucinations, central nervous system depression, convulsions, respiratory and cardiac arrest, and death.Antihistamines may diminish mental alertness; conversely, particularly, in the young child, they may occasionally produce excitation.CNS DepressantsAntihistamines may have additive effects with alcohol and other CNS depressants, e.g., hypnotics, sedatives, tranquilizers, antianxiety agents.Activities Requiring Mental AlertnessPatients should be warned about engaging in activities requiring mental alertness and motor coordination, such as driving a car or operating machinery.Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients (see PRECAUTIONS, Geriatric Use).

The following US Branded drugs contain Cyproheptadine Hydrochloride

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PERIACTIN -- MERCK AND CO INC

CYPROHEPTADINE HYDROCLORIDE -- STASON PHARMACEUTICALS INC