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Carcinoma of the Large Intestine


Is a Neoplastic Process.

"A carcinoma arising from the colon or rectum. Among both males and females, it is the second most common visceral malignancy in the United States, with an expected 185,000 new cases each year. It is considered as a disease of Western-world lifestyle. Grossly, most colorectal carcinomas are either polypoid or of the ulcerative-infiltrating type. Adenocarcinoma is the most common carcinoma in the colon and rectum. Colorectal adenocarcinoma can be divided in three grades: Grade I (low grade or well-differentiated), grade II (average grade or moderately differentiated) and grade III (poorly differentiated). The following histopathologic features have been shown to be prognostic indicators in multivariate analysis: microacinar versus macroacinar growth pattern, endocrine cells detected by chromogranin immunohistochemistry, Crohn's-like reaction and tumor budding. The standard therapy for colorectal carcinoma is surgical resection. The 5-year crude survival rate after curative resection for colorectal carcinomas ranges between 40% and 60% in most large series (Sternberg's Diagnostic Surgical Pathology, 3rd ed., 1999)."

Related Topics
Related Medication
The following information has been extracted from US Food and Drug Administration databases. It shows drugs which may be used to treat this condition, and those drugs whose use may be dangerous with this condition. This is informational only. You must consult a physician for your particular case. You may click on a listed drug for further information.

The following medications may be indicated for this condition

ELOXATIN
Leucovorin Calcium
Xeloda

The following medications may be hazardous when used with this condition

Leucovorin Calcium

This web-site is for informational purposes only and is not intended as a substitute for advice from your doctor. It should not to be used for self-diagnosis or treatment.