"A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)"
The following medical topics are often discussed with Amyotrophic Lateral Sclerosis on the web pages we have analyzed and so may be medically related.
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The following information has been extracted from US Food and Drug Administration databases.
It shows drugs which may be used to treat this condition, and those drugs whose use may be dangerous with this condition.
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The following medications may be indicated for this condition