Name: Amyotrophic Lateral Sclerosis

Description: Lou Gerhig's Disease

This casebook is published and has been read 1176 times.

The author of this casebook has identified the following medical topics as being highly relevant to this casebook.

  • Amyotrophic Lateral Sclerosis -- A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
Bookmarks The following information, which has been distilled by the casebook author from this and other websites is particularly relevant to this casebook.
Bookmarks - Web
Web Page Notes Concepts
 Welcome - The ALS Association Great overview from the ALS Association. Also has links to current research (Amyotrophic Lateral Sclerosis)
 Amyotrophic Lateral Sclerosis Fact Sheet: National Institute of Neurological Disorders and Stroke (NINDS) Reliable information from National Institute of Neurologic Illnesses and Stroke (Amyotrophic Lateral Sclerosis)
 Amyotrophic lateral sclerosis (ALS) - Good overview from Mayo Clinic (Amyotrophic Lateral Sclerosis)
 MedlinePlus: Amyotrophic Lateral Sclerosis From Medline Plus- includes an interactive tutorial (Amyotrophic Lateral Sclerosis)

This web-site is for informational purposes only and is not intended as a substitute for advice from your doctor. It should not to be used for self-diagnosis or treatment.