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Name: Autoimmunity and CNS disorders

Description: Brain diseases including mental health

This casebook is published and has been read 115 times.

The author of this casebook has identified the following medical topics as being highly relevant to this casebook.

  • Epilepsy -- A disorder characterized by recurrent episodes of paroxysmal brain dysfunction due to a sudden, disorderly, and excessive neuronal discharge. Epilepsy classification systems are generally based upon: (1) clinical features of the seizure episodes (e.g., motor seizure), (2) etiology (e.g., post-traumatic), (3) anatomic site of seizure origin (e.g., frontal lobe seizure), (4) tendency to spread to other structures in the brain, and (5) temporal patterns (e.g., nocturnal epilepsy). (From Adams et al., Principles of Neurology, 6th ed, p313)

  • autoimmunity -- Process whereby the immune system reacts against the body's own tissues. Autoimmunity may produce or be caused by AUTOIMMUNE DISEASES.

  • Limbic Encephalitis -- A paraneoplastic syndrome marked by degeneration of neurons in the medial temporal lobe. Clinical features include behavioral changes, HALLUCINATIONS, loss of short term memory, anosmia, AGEUSIA, and DEMENTIA. Circulating anti-neuronal antibodies (anti-Hu; also called ANNA 1) and small cell lung carcinomas are frequently associated with this condition. (From Pathologe 1997 Sep;18(5):406-10; J Int Neuropsychol Soc 1996 Sep;2(5):460-6; Brain 1997 Jun;120(Pt 6):923-8)

  • Encephalitis -- Inflammation of the BRAIN due to infection, autoimmune processes, toxins, and other conditions. Viral infections (see ENCEPHALITIS, VIRAL) are a relatively frequent cause of this condition.

Bookmarks The following information, which has been distilled by the casebook author from this and other websites is particularly relevant to this casebook.
Bookmarks - Web
Web Page: nformation and LinkNotesConcepts
 Autoantibodies associated with psychiatric disorde...[Curr Neurovasc Res. 2006] - PubMed Result discusses the possible role of autoantibodies related to the psychiatric manifestations in autoimmune diseases (autoimmunity)
 
 New autoantibody mediated disorders of the central...[Curr Opin Neurol. 2003] - PubMed Result There is much that needs to be done to define the role of these antibodies and to determine how they affect central nervous system function (autoimmunity)
 
 Autoantibody-mediated disorders of the central ner...[Autoimmunity. 2008] - PubMed Result Are autoantibodies the cause or effect of CNS diseases? (autoimmunity)
 

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